Interferon Discussion

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1. In this discussion, you are expected to extensively research (read chapter 6 of – The Molecular Basis of Cancer textbook by Mendelsohn et. al.) and write on the topic – The Role of Infectious Agents in Oncogenesis. You are required to use this outline as a guide (do not restrict yourself to it, though).

  • Introduction and history of infectious agents and oncogenesis
  • Identify at least five (5) infectious agents that play a role in oncogenesis

For each infectious agent, discuss the following;

  • What cancer(s) is associated with its development?
  • What is(are) the oncogenic factor(s) in the infectious agent?
  • What is(are) the mechanism(s) of oncogenesis
  • What are your suggestions for prevention, control and or treatment of any of these cancers?

2.In this Discussion, you are expected to read chapter 53 of – The Molecular Basis of Cancer textbook by Mendelsohn et. al. and write a thread on “How Useful are Interferons Interferon in Oncology?” You are expected to use the outline below in your writing;

  • What are interferons?
  • Do interferons contribute to oncogenesis (if yes, then how exactly)?
  • With pertinent examples, describe these antitumor effects of interferons;
    • Pro-apoptosis
    • Immune effects
    • Inhibition of metastasis
    • Inhibition of angiogenesis
 
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